The RCAN1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to csp1, DSCR1, MCIP1, and Rcan1. This antibody recognizes Human, Mouse, and Rat antigen. The RCAN1 Antibody has been validated for the following applications: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants